Buy Stelara Injection Online – Advanced Treatment for Psoriasis and Crohn’s Disease

What is Stelara?

Stelara (ustekinumab) is used to treat several autoimmune disorders, including plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Stelara injection is an interleukin inhibitor that works by inhibiting IL-12 (interleukin-12) and IL-23 (interleukin-23), two proteins in your body that induce inflammation in autoimmune disorders. Stelara acts by inhibiting the action of IL-12 and IL-23, reducing inflammation, discomfort, edema, and other skin complaints.

Stelara is typically administered as a subcutaneous injection; however, for Crohn’s disease and ulcerative colitis, the initial dosage is administered as an IV infusion.

Stelara was first approved by the FDA on September 25, 2009, for individuals with moderate to severe psoriasis, and its use has now expanded to encompass other disorders. Stelara is a biologic drug that was the first brand of ustekinumab to receive FDA approval, hence the name “reference product.” Wezlana, an interchangeable biosimilar to ustekinumab, was authorized on October 31, 2023.

Uses of Stelara Injection

Stelara injection (ustekinumab) is a biologic medication used to treat moderate to severe plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Stelara works by targeting two specific proteins—interleukin-12 (IL-12) and interleukin-23 (IL-23)—that are involved in the body’s inflammatory response. By blocking these proteins, Stelara reduces the inflammation that leads to the skin symptoms of psoriasis and the digestive symptoms of Crohn’s disease, providing relief for patients who have not responded to other treatments.

• Plaque psoriasis (moderate to severe) in patients 6 years and older who are candidates for phototherapy or systemic therapy.
• Psoriatic arthritis (active) in patients 6 years and older.
• Crohn’s disease (moderately to severely active) in adults.
• Ulcerative colitis (moderately to severely active ) in adults.

How Stelara Injection Works

Stelara works by inhibiting the activity of interleukin-12 (IL-12) and interleukin-23 (IL-23), proteins that play a key role in immune system overactivation. In conditions like psoriasis and Crohn’s disease, the immune system mistakenly attacks healthy tissues, leading to inflammation and damage. By targeting these specific pathways, Stelara helps control this immune response, reducing symptoms like skin plaques, joint pain, and intestinal inflammation. It is administered as a subcutaneous injection and typically requires dosing every 8 to 12 weeks.

How should I use Stelara Injection?

how to inject stelara injection

Before you begin therapy with this medication, your doctor may do tests to ensure that you do not have tuberculosis or other illnesses.

Follow the recommendations on your prescription label and read any drug guidelines or instruction sheets. Use the medication precisely as instructed. Stelara should only be used as directed by your doctor. Prepare your injection just when you’re ready to administer it. Do not use if the drug is foggy, has changed color, or contains particles. Contact your pharmacist for new medication.

For Crohn’s disease and ulcerative colitis, your healthcare professional will administer the initial dose of Stelara via a vein in the arm (intravenous infusion) in a healthcare facility. It takes at least an hour to receive the infusion. Your future doses will be administered as a subcutaneous injection.

Stelara is administered as a subcutaneous injection under the skin to treat psoriasis or psoriatic arthritis, as explained below.

Injecting Stelara under the skin:

• This medication should be administered by a healthcare provider in children aged 6 and up.
• If your doctor agrees that you or a caregiver can give your Stelara injections at home, you should be trained on how to properly prepare and inject the medication.
• Your doctor will establish the appropriate dose for you, the amount of each injection, and how frequently you should have it. Your dosage requirements may fluctuate as you gain or lose weight.
• Your doctor or nurse should show you or your caregiver how to use an injection before you try it yourself.
  Stelara should be injected under the skin in your upper arms, buttocks, upper legs (thighs), or abdomen.
• Do not administer an injection to any area of the skin that is painful, bruised, red, or hard.
• This medication should be administered at a separate injection location each time.
• Use a needle and syringe only once and then store them in a puncture-proof “sharps” container. Follow state or local rules regarding how to dispose of this container. Keep it out of the reach of kids and dogs.

Stelara Injection Dosage

Crohn’s Disease and Ulcerative Colitis Stelara is administered as an infusion for the initial dose and then as a subcutaneous injection every 8 weeks thereafter.

Stelara is administered as a subcutaneous injection first and four weeks later, followed by a dose every 12 weeks.

The dose is based on the patient’s weight.

Body Weight of Patient at the time of dosing	Dose	Number of 130 mg/26 mL (5 mg/mL) STELARA ®vials
55 kg or less	260 mg	2
more than 55 kg to 85 kg	390 mg	3
more than 85 kg	520 mg	4

Stelara Dosage in Plaque Psoriasis

Subcutaneous Adult Dosage Regimen

• For individuals weighing 100 kg or less, the suggested dose is 45 mg at first and 4 weeks later, followed by 45 mg every 12 weeks.
• The suggested dose for people weighing more than 100 kg is 90 mg at first and 4 weeks later, followed by 90 mg every 12 weeks.

Subcutaneous Pediatric Dosage Regimen

The recommended STELARA® dose for pediatric patients (6-17 years old) with plaque psoriasis is based on body weight.

Body Weight of Patient at the Time of Dosing	Recommended Dose
less than 60 kg	0.75 mg/kg
60 kg to 100 kg	45 mg
more than 100 kg	90 mg

Stelara is available in:

Subcutaneous Injection

• Stelara 90 mg/mL single-dose prefilled syringe

Intravenous Infusion

• single-dose vial 130 mg/26 mL (5 mg/mL)

Storage of Stelara

Diluted Stelara infusion

• If necessary, the diluted infusion solution can be stored at room temperature for up to 7 hours at 25°C (77°F).
• After preparing the diluted solution, the storage duration at room temperature begins.
• The infusion should be completed within 8 hours of dilution in the infusion bag (total time after preparation including storage and infusion).
• Don’t freeze.
• Discard any unused infusion solution.

Stelara vials, prefilled syringes

• Store vials and prefilled syringes in a refrigerator at 36°F to 46°F (2°C to 8°C).
• Vials should be kept standing up straight.
• This drug should be stored in its original box to avoid light exposure until it is time to use it.
• Don’t freeze, Don’t shake.
• Stelara prefilled syringes can be stored at room temperature up to 30°C (86ºF) for up to 30 days in their original carton to prevent light exposure. On the container, write the date when the prefilled syringe was first retrieved from the refrigerator. A syringe that has been stored at ambient temperature should not be returned to the refrigerator. If the syringe has not been used within 30 days of room temperature storage, discard it.
• Do not use this medication after the expiration date listed on the box or prefilled syringe.

Stelara Side Effects

• cough with mucus
• headache, tiredness
• redness at the injection site
• fever, flu-like symptoms
• infection
• itching
• stomach pain, nausea, diarrhea
• vaginal itching or discharge

Serious Stelara side effects:

If you have the following symptoms of an allergic response to Stelara: hives, chest pain, difficulty breathing, lightheadedness, swelling of your face, lips, tongue, or neck, get emergency medical attention.

Benefits of Stelara for Psoriasis and Crohn’s Disease

Stelara provides significant relief for patients with chronic autoimmune conditions such as psoriasis and Crohn’s disease. Patients often experience a reduction in symptoms such as skin scaling, redness, joint pain, and gastrointestinal discomfort. For those with Crohn’s disease, Stelara helps maintain remission and prevent flare-ups. It offers a long-lasting solution with fewer injections compared to other treatments. However, patients should be aware of potential Stelara side effects, which can include infections, headache, and fatigue. Regular monitoring by a healthcare provider is essential during treatment.

FAQ

How to give Stelar injection video

how to inject stelara injection

Why is Stelara so expensive?

Biologic medications can be expensive due to the extensive research and testing required to ensure their safety and efficacy. A biologic drug’s maker has up to 12 years to sell the product. When the biologic drug’s patent expires, competing pharmaceutical companies can market biosimilar versions. You can get Stelara injections on our website at $1900.

Is Stelara bad for your liver?

Ustekinumab-related liver damage is rare and mild. From a hepatic standpoint, the drug looks to be safe, even in individuals with pre-existing liver illness or those who have previously experienced impaired liver function while taking other medications.